Second-Generation Antipsychotic Drugs for Children and Adolescents
نویسندگان
چکیده
The effectiveness and safety of antipsychotics have not been fully established in children adolescents. Many approved for use adults are prescribed off-label to We investigated the tolerability adolescents with schizophrenia bipolar disorder. A literature review empirical evidence regarding antipsychotics, particularly second-generation showed that these drugs were safe effective this population. Antipsychotics similarly treatment disorder When prescribing population, clinicians should consider adverse events discontinuation rate treated patients. However, current shows a lack consensus
منابع مشابه
Second-generation antipsychotic medications in children and adolescents.
OBJECTIVE We reviewed available pediatric literature on second-generation antipsychotic medications to assess current evidence of efficacy and safety. METHOD An English language MEDLINE search (1974-2003) was conducted using key words-atypical antipsychotics, children and adolescents, toxicity, clozapine, risperidone, olanzapine, quetiapine, ziprasidone, and aripiprazole. Additional efficacy ...
متن کاملCorrection: Hyperprolactinemia with antipsychotic drugs in children and adolescents
1. Reference 19 in the original article [1] (Frazier JA, et al. Risperidone treatment for juvenile bipolar disorder: a retrospective chart review. J Am Acad Child Adolesc Psychiatry. 1999;38:960–5) was quoted as indicating that one of the 9 of 11 outpatients aged 4–17 years treated with risperidone who developed hyperprolactinemia had amenorrhea and one had gynecomastia. In fact, the only hyper...
متن کاملHyperprolactinemia with Antipsychotic Drugs in Children and Adolescents
There is increasing use of antipsychotic drugs in pediatric and psychiatry practice for a wide range of behavioral and affective disorders. These drugs have prominent side effects of interest to pediatric endocrinologists, including weight gain and associated metabolic risk factors and hyperprolactinemia. The drugs block dopamine action, thus disinhibiting prolactin secretion. Hyperprolactinemi...
متن کاملCardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents.
CONTEXT Cardiometabolic effects of second-generation antipsychotic medications are concerning but have not been sufficiently studied in pediatric and adolescent patients naive to antipsychotic medication. OBJECTIVE To study the association of second-generation antipsychotic medications with body composition and metabolic parameters in patients without prior antipsychotic medication exposure. ...
متن کاملSecond-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis.
BACKGROUND Because of the debate about whether second-generation antipsychotic drugs are better than first-generation antipsychotic drugs, we did a meta-analysis of randomised controlled trials to compare the effects of these two types of drugs in patients with schizophrenia. METHODS We compared nine second-generation antipsychotic drugs with first-generation drugs for overall efficacy (main ...
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ژورنال
عنوان ژورنال: Journal of Nippon Medical School
سال: 2021
ISSN: ['1347-3409', '1345-4676']
DOI: https://doi.org/10.1272/jnms.jnms.2021_88-108